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Rui Fu

I have studied various aspects of RNA-related gene expression regulation processes, including transcription, translation, and especially RNA degradation. In lieu of bench experience, I have now worked several years in bioinformatic roles analyzing high throughput sequencing data.

Education

Ph.D. Biological Science

University of California San Diego

La Jolla, CA

2015 - 2009

B.S. Biological Science

Xiamen University

Xiamen, China

2009 - 2005

Research Experience

Bioinformatic tool development: 1) clustifyr, single cell RNA-seq cell identity assignment (author); 2) valr, tidyverse-style genomic interval analysis (co-developer); 3) scraps, extraction of polyadenylation site info from scRNA-seq data (co-developer)

Postdoctoral Informatics Fellow

Jay Hesselberth’s Supervision

University of Colorado Anschutz

Current - 2017

  • Development of bioinformatics R packages
  • RNA-seq and transcript annotation improvements for ground squirrel hibernation
  • Informatics support on various collaborations

Postdoctoral Research Fellow

Judy Lieberman’s Lab

Harvard Medical School

2017 - 2016

  • Identification of the mitochondrial trigger of apoptotic mRNA decay

Graduate Research Assistant

Jens Lykke-Andersen’s Lab

University of California San Diego

2015 - 2009

  • Investigation of co-factors involved in TTP-mediated mRNA decay and translational repression during the immune response of macrophages
  • Characterization of the roles of TTP family proteins in cell cycle progression regulation of mouse embryonic fibroblasts

Undergraduate Research Assistant

Ruichuan Chen’s Lab

Xiamen University

2009 - 2007

  • Exploration of cell cycle and apoptosis implications of the transcription elongation regulator HEXIM1
  • Characterization of molecular mechanism of p-TEFb activation by HIV-Tat

Teaching Experience

I have actively sought out teaching and mentoring experiences, as well as training opportunities to improve my teaching skills.

RNA Bioscience Initiative Office Hour

University of Colorado Anschutz

Denver, Colorado

Current - 2018

  • Weekly office hour open to students and researchers with informatics questions on campus

Lecture Instructor (Graduate Level Courses)

University of Colorado Anschutz

Denver, Colorado

Current - 2018

  • Lecture for RNA sequencing section of Rigor in Research (2020)
  • Lectures and paper discussion for RNA section of Foundations in Biomedical Sciences (2018, 2019)
  • Lectures for Practical Data Analysis with R/RStudio (2018, 2019)
  • Workshop for scRNA-seq Data Analysis (2019)

Summer Research Mentoring

Harvard Medical School

Boston, Massachusetts

2017

  • Mentoring of research and scientific writing for high school student enrolled in the MIT Research Science Institute program

BS/MS Student Research Mentoring

University of California San Diego

La Jolla, CA

2015 - 2013

  • Mentoring of student research for undergraduate honor thesis and master thesis projects
  • Mentee was awarded best poster presentation at 2014 Biological Sciences Annual Student Research Showcase

Teaching assistant

University of California San Diego

La Jolla, CA

2012 - 2011

  • Molecular Biology
  • DNA Recombination Lab

Publications, as First Author

mRNA processing in the brain of a heterothermic mammal during hibernation

In preparation for submission

N/A

2020

  • Gillen A*, Fu R*, Riemondy K, Hesselberth J, Martin, S.

clustifyr: an R package for automated single-cell RNA sequencing cluster classification

F1000Research

N/A

2020

  • Fu R, Gillen A, Sheridan R, Tian C, Daya M, Hao Y, Hesselberth J, Riemondy K.

PNPT1 release from mitochondria during apoptosis triggers decay of poly(A) RNAs

Cell

N/A

2018

  • Liu X*, Fu R*, Pan Y, Meza-Sosa K, Zhang Z, Lieberman J.

Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements

RNA

N/A

2016

  • Fu R, Olsen MT, Webb K, Bennett EJ, Lykke-Andersen J.

Publications, as Contributing Author

Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Acute Myeloid Leukemia Patients

Cancer Discovery

N/A

2019

  • Pei S, Pollyea D, Gustafson A, Stevens B, Minhajuddin M, Fu R, Riemondy K, Gillen A, Sheridan R, Kim J, Costello J, Amaya M, Inguva A, Winters A, Ye H, Krug A, Jones C, Adane B, Khan N, Ponder J, Schowinsky J, Abbott D, Hammes A, Myers J, Ashton J, Nemkov T, D’Alessandro A, Gutman J, Fesik S, Ramsey H, Savona M, Smith C, Jordan C.

Chronic Liver Disease in Humans Causes Expansion and Differentiation of Liver Lymphatic Endothelial Cells

Frontiers in Immunology

N/A

2019

  • Tamburini, BAJ, Finlon JM, Gillen A, Kriss MS, Riemondy K, Fu R, Schuyler R, Hesselberth J, Rosen HR, Burchill MA.

Single cell RNA Sequencing Identifies Transforming Growth Factor ß as a Critical Regulator of Alveolar Regeneration

JCI Insight

N/A

2019

  • Riemondy K, Jansing N, Jiang P, Redente E, Gillen A, Fu R, Anthony G, Hesselberth J, Zemans R.

Recovery and analysis of transcriptome subsets from pooled single-cell RNA-seq libraries.

Nucleic Acid Research

N/A

2019

  • Riemondy K, Ransom M, Alderman C, Gillen A, Fu R, Finlay-Schultz J, Kirkpatrick G, Di Paola J, Kabos P, Sartorius C, Hesselberth J.

Posters and Talks

ClustifyR: automated single-cell RNA sequencing cluster classification

Keystone Symposia on Single Cell Biology (Poster)

N/A

2019

PNPT1 release from the mitochondrial intermembrane space triggers rapid decay of mRNA and poly(A)-tailed ncRNA during apoptosis

Boston Children’s Hospital PCMM Research Poster Session (Poster)

N/A

2017

PNPT1 release from the mitochondrial intermembrane space triggers rapid decay of mRNA during apoptosis

2016 Boston Children’s Hospital PCMM Research Poster Session (Poster)

N/A

2016

TTP-mediated mRNA repression involves recruitment of the 4EHP-GYF2 complex

Cold Spring Harbor Laboratory mRNA Processing Meeting (Presentation)

N/A

2015

TTP represses translation of target mRNAs through the 4EHP-GYF2 complex

UCSD Mechanisms of Gene Expression Seminar (Presentation)

N/A

2014

TTP family proteins regulate the stability of retinoblastoma protein mRNAs during serum-stimulated G0-S transition

Cold Spring Harbor Laboratory mRNA Processing Meeting (Poster)

N/A

2013

The regulation of TTP family mRNA-decay factors during G0-S cell cycle progression

Keystone Symposia on Protein-RNA Interactions (Poster)

N/A

2012

Service, Training, Recognition

GENETICS Early Career Reviewer

N/A

N/A

Current - 2018

Admissions Committee Member for CU Graduate Experiences for Multicultural Students

N/A

N/A

2019

BioFrontiers Hackathon

N/A

N/A

2018

Harvard Medical School Scientists Teaching Science Course

N/A

N/A

2016

Dr Huang Memorial Scholarship

N/A

N/A

2011 - 2009

National College Students Creativity Experiment Project

N/A

N/A

2009 - 2007

University Merit Student, First-Class Scholarship

N/A

N/A

2008 - 2006

Disclaimer

Made with pagedown.

github.com/raysinensis/cv.

Last updated on 2020-05-15.